Monday, December 30

Louis Pasteur | Biography, Discoveries, Facts & Death

Louis Pasteur (Born on December 27, 1822, in Dole, Jura, France – Died on  September 28, 1895, in Marnes-la-Coquette, France) was a French biologist, microbiologist, physicist, and chemist whose discoveries had enormous importance in the history of chemistry and medicine.

He is recognized for his remarkable discoveries of the causes and prevention of diseases. Among his most notable achievements can mention the reduction of mortality and the creation of the first vaccine against rabies (rabies vaccine).

Their experiments provided a basis for the microbiological theory of the disease. He was best known to the general public for inventing a method to prevent milk and wine from causing disease, a process that came to be called pasteurization, in honor of his surname.

Pasteur is considered to be one of the three main founders of microbiology, along with Ferdinand Cohn and Robert Koch. He also made many discoveries in the field of chemistry, mainly the molecular basis for the asymmetry of certain crystals.

He was the founder and director of the institute named after the Luis Pasteur Institute established in 1887, a private French non-profit foundation dedicated to the study of biology, microorganisms, diseases, and vaccines.

louis pasteur discoveries

Quick Facts of Louis Pasteur

  • Born: December 27, 1822, Dole, Jura, France
  • Died: September 28, 1895 (aged 72) Marnes-la-Coquette, France
  • Known for: Created the first vaccines for rabies:-
    (Cholera vaccine)
    (Anthrax vaccines)
    (Pasteurization)
  • Awards:
    Legion of Honor Grand Cross (1881)
    Rumford Medal (1856)
    Foreign Member of the Royal Society (1869)[2]
    Copley Medal (1874)
    Albert Medal (1882)
    Foreign Associate of the National Academy of Sciences (1883)
    Cameron Prize for Therapeutics of the University of Edinburgh (1889)
    Leeuwenhoek Medal (1895)
    Order of the Medjidie
  • Fields:
    Biology
    Microbiology
    Chemistry
  • Institutions:
    University of Strasbourg
    University of Lille
    École Normale Supérieure
    Pasteur Institute
  • Nationality: French
  • Spouse: Marie Pasteur
  • Children: Marie-Louise Pasteur
  • Parents: Father – Jean-Joseph Pasteur, Mother – Jeanne-Etiennette Roqui
  • Religion: Catholic Christianity
  • Quotes: Science knows no country, because knowledge belongs to humanity, and is the torch which illuminates the world. – Louis Pasteur

Early Life of Louis Pasteur

Louis Pasteur was born at two in the morning on December 27, 1822, in the family home of Dole, the third child of Jean-Joseph Pasteur and Jeanne-Étiennette Roqui. He was baptized in the Collegiate Church of Notre-Dame de Dole on January 15, 1823.

His father, after having been a sergeant in the Napoleonic army, resumed the family profession of tanner. In 1827, the family left Dole for Marnoz, the place of the Roqui 3 family house, to finally move to a new house in 1830 in Arbois, a locality more conducive to tanning activity.

The young Pastor follows mutual education courses in Arbois then enters the town college. It was at this time that he became known for his talents as a painter; he also made numerous portraits of members of his family and the inhabitants of the small town.

Education

Louis Pasteur went to the royal high school in Besançon. Then in October 1838, he left for the Institution Barbet, in Paris, in order to prepare for the baccalaureate and then for the competitive examinations. However, depressed by this new life, he gave up his project, left Paris, and finished his school year 1838-1839 at the college of Arbois.

At the start of the 1839 school year, he returned to the Royal College of Franche-Comté, in Besançon. In 1840, he obtained the baccalaureate in letters and then, in 1842, after a failure, the baccalaureate in mathematical sciences.

Louis Pasteur returns to Paris in November. Housed at the Barbet pension, where he also acts as a tutor, he follows courses at the Lycée Saint-Louis and enthusiastically attends those given at the Sorbonne by the chemist Jean-Baptiste Dumas; he was also able to take some lessons with Claude Pouillet.

In 1843, he was finally admitted – fourth – to the Normal School. Later he will be a student of Jean-Baptiste Boussingault at the National Conservatory of Arts and Crafts.

Developing Rabies Vaccine

louis pasteur vaccines

Louis Pasteur developed a virus vaccine against rabies disease. He managed to make a dog immune, and he treated horses. On July 6, 1885, nine-year-old Joseph Meister from Alsace, who had been bitten by a mad dog, was brought to Pasteur.

Pasteur began the treatment with the help of inoculations developed by him, which was personally risky for him, as he was not a licensed physician. After weeks of treatment of the young patient, who was flushed with fever, the boy healed and Pasteur could rightly say that he had overcome rabies.

Pasteur was known as a devout Christian, who prayed intensively every day, including the rosary. He died at the age of 72 and was buried in the Notre-Dame Cathedral of Paris, but his body was moved fairly soon afterward to a crypt of the Catholic chapel in the Pasteur Institute in Paris.

Controversy with Robert Koch

1882 was a very interesting year for Pasteur as disputes continued to arise with other scientists on topics that now seemed indisputable. The German Health Bureau’s work magazine had conducted, under the direction of Robert Koch, a real campaign against Pasteur, denying the preservative influence of vaccination.

Pasteur then asked that experiments be made before a commission appointed by the German government. After the congress, all the members of the assembly who did not share his views had to change their mind; this fact, however, did not stop Koch’s attacks, who continued to disregard Pasteur’s discovery of the office of earthworms in the etiology of anthrax.

Awards and Honors

Pasteur Nobel Prize Winner
Louis Pasteur Nobel Prize Winner

In 1883 Pasteur was elected to the American Academy of Arts and Sciences and the National Academy of Sciences. The Pasteur Institute was founded in 1887. Pasteur lived in the first building of the institute during the last years of his life (from 1888).

The Pasteur Museum has been located in the part of this building since 1936. Other museums exist in his former homes in Dole and Arbois (see Maison de Louis Pasteur). Numerous monuments have been erected in his honor. At times, Pasteur was considered the most important Frenchman who ever lived in French polls before Napoleon.

While his memory was cherished in Germany, Pasteur was especially popular in Russia. Tsar Alexander III was one of the most generous donors for the Pasteur Institute with a contribution of 100,000 francs.

Numerous Russian scientists came to Paris, among them the future Nobel Prize laureate Ilya Metschnikow, in whose section at the Pasteur Institute a Russian colony was temporarily formed.

The bacteria family of the Pasteurellaceae with the genus Pasteurella is named after Pasteur. The diseases caused by Pasteurella multocida are known as “pasteurellosis”. The asteroid (4804) Pasteur also bears his name.

His college in Arbois, a place in Algeria and a district in Canada was named after Pasteur. More than 2000 streets in France bear his name, including Boulevard Pasteur, a major thoroughfare in Paris.

The metro goes to the Pasteur station there. The Pasteur Peninsula and Pasteur Island in Antarctica also bear his name in his honor. The passenger ship Pasteur, commissioned in 1939, was also named after him.

The Louis Pasteur Medal, also named after him, is a renowned scientific honor for medical professionals. It was awarded by the Louis Pasteur University of Strasbourg before 2009.

Great discoveries of Louis Pasteur

It is significant to note that all the great discoveries of the French scientist were made by addressing the most serious problems, in the mid-nineteenth century, of agriculture, the agricultural industry, and livestock. The succession of the same discoveries corresponds to a succession of studies on agricultural, agro-industrial, veterinary problems:

  • Abnormalities of the fermentation of beer (1854);
  • Fermentation of wine and vinegar (1861 -62);
  • Pasteurization (1862);
  • Alterations of the wine of fungal or bacterial origin (1863 -64);
  • Silkworm diseases (1865 -70);
  • Chicken cholera (1880);
  • Carbuncle of cattle, sheep, horses (1881);
  • Sylvan anger and serotherapy.

Death

In 1868, Pasteur suffered a severe brain stroke that paralyzed the left side of his body, but he recovered. A stroke or uremia in 1894 severely impaired his health. Failing to fully recover, he died on 28th September 1895, in Marnes-la-Coquette near Paris.

Pasteur was given a state funeral and was buried in the Cathedral of Notre Dame, but his remains were reinterred in the Pasteur Institute in Paris, in a vault covered in depictions of his accomplishments in Byzantine mosaics.

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